Safe Lab Practices Guide: PPE, Chemical Handling & Emergency Safety

Safe lab practices start with non-negotiable PPE, clear labeling, and emergency readiness. Every item, from goggles to worktops, plays a role in preventing accidents. A clean, organized lab layout supports these habits and turns safety from a rule into a routine.

Bullet Point Lab Safety Checklist:

  • Wear proper PPE: lab coat, gloves, sealed goggles, closed-toe shoes

  • Tie back hair, remove jewelry and acrylic nails

  • Keep workspaces clean and free of clutter

  • Label all chemical containers clearly (name, hazard, date)

  • Store incompatible chemicals separately

  • Use flammable storage cabinets for volatile materials

  • Operate fume hoods correctly; never use them for storage

  • Maintain emergency gear: extinguisher, eyewash, shower, spill kit

  • Know emergency protocols; rehearse regularly

  • Never wear headphones or allow horseplay in the lab

  • Dry glassware on pegboards, not on benches

  • Wash hands after lab work—even if gloves were worn

  • Lead by example; enforce rules through behavior, not posters

Scroll down to find the full safety checklist, recommended materials, and product-backed layout tips for better prevention and peace of mind.

Why Lab Safety Is Non-Negotiable

Cut corners in a lab, and it doesn’t take long for reality to punch through the paperwork. We’ve seen it happen, one team stored incompatible chemicals side by side to save shelf space. A month later, a cracked cap turned that shortcut into a full-blown spill that nearly shut down their facility. 

Or the lab that ran equipment 24/7 on a wobbly bench near the edge of a work surface. The machine overheated, tipped, and took half the workstation with it. All preventable. All expensive.

The consequences stretch far beyond a ruined countertop or a missed experiment. A single overlooked safety step can spiral into medical costs, equipment loss, code violations, or even lawsuits. And that’s not theoretical, it’s the kind of real risk that shows up when safety becomes a checkbox instead of a culture.

Products like our epoxy resin countertops are chosen not just for durability, but because they perform under pressure, literally and figuratively.

Educators are under pressure too.

One mishap in a student lab can trigger insurance audits, parent complaints, or worse. And for institutions, compliance violations are costly in more ways than one. Whether you’re training high school students or outfitting a university-level chemistry wing, safety is the contract between everyone who uses the space.

Personal Protective Equipment (PPE): What You Really Need

Some people still think safety gear is optional. We’ve heard the excuses, “It’s a quick test,” or “I’m not handling anything dangerous.” But accidents don’t wait for complexity. PPE isn’t about paranoia. It’s about minimizing risk when things go sideways, even during basic tasks.

Must-Have Gear for Every Lab Environment

Let’s talk lab coats. Even in short experiments, they provide a barrier against splashes, particulates, and the occasional bump into a chemical-soaked surface. Skip the coat, and you’re betting your skin against the bench.

Gloves, goggles, and closed shoes make up the holy trinity of lab safety. No matter your role, student, researcher, or supervisor, these are baseline requirements. Open shoes? That’s an invitation for burns. 

Bare hands? 

Welcome to chemical absorption. Goggles might fog, but they’re a minor inconvenience compared to what happens when peroxide lands in your eye.

Hair tied back, jewelry off, acrylic nails removed. All of it matters. Anything that can catch, melt, or dangle has no place near flames, solvents, or live wires.

Can I Wear Contacts in the Lab?

This comes up often, and the answer is a cautious maybe. Contacts can trap harmful vapors or chemicals against the eye, worsening exposure. Some labs allow them under tightly fitted goggles, but it depends on the setting. If you must wear contacts, invest in high-quality goggles that fully seal without pressure gaps. And always have a backup pair of glasses nearby. The real issue isn’t the lenses, it’s whether your gear accounts for them.

What Labs Actually Provide

PPE doesn’t stop at what you wear, it includes the surfaces you lean on and the tools you use. That’s why labs that work with harsh compounds choose materials that won’t react under pressure. Surfaces like phenolic resin worktops are built to resist chemical splashes, meaning when something does spill, you’ve got a buffer between you and the damage.

PPE-ready environments matter. A steel base table won’t save your sample from acid. A resin one might. It’s one thing to dress for safety. It’s another to work in a space that’s built for it.

Clean Workspaces, Clear Thinking: Housekeeping for Safety

Messy labs invite mistakes. Glassware gets knocked over, cords get tangled, and chemical residue turns into an afterthought. The state of your bench says a lot about your process. Sloppy means slow. It also risks the entire experiment, and sometimes the people around you.

Lab Clutter = Accidents Waiting to Happen

Everything on your bench should earn its place. If it’s not part of the current task, it’s a liability. 

That extra beaker? 

One elbow away from a spill. The open laptop next to a solvent bottle? Just one splash away from being both toxic and expensive.

And then there’s the wildcard, working with someone who doesn’t clean as they go. You can follow every rule in the book, but if your lab partner leaves containers uncapped or tools in weird places, they turn your setup into a hazard zone. 

Best advice? 

Speak up early, set boundaries, and build a culture of accountability before something breaks or burns.

Tools, Glassware, and Pegboards

Drying racks and pegboards aren’t extras. They’re part of the safety system. When glassware piles up in the sink or sits wet on the bench, you’re looking at contamination risk, not to mention breakage.

That’s why we make chemical-resistant pegboards in epoxy, phenolic, and stainless steel. They help glassware dry quickly and safely, without absorbing residues or warping over time. And every one of them comes with a year of free replacement pegs, because if your tools are maintained, your system works better. Period.

Post-Experiment Hygiene

Once the data’s collected, your job’s not done. Wash your hands thoroughly, even if you wore gloves. Wipe down your bench, especially if chemicals were used. And skip the snack until you’ve left the workspace. Labs aren’t dining rooms, and that leftover caffeine in your beaker might not be coffee.

Clean labs do more than meet code. They prevent exposure, keep you sharp, and build habits that carry across every environment you’ll ever work in.

Chemical Handling Rules Everyone Must Follow

Photo Source -> ThoughtCo.

If you’re working with chemicals, you’re managing risk. And that risk increases every time you skip a label, rush a transfer, or cut corners on storage. Safe handling isn’t about paranoia, it’s a system of habits that stops problems before they start.

Label Everything, Always

Every beaker, bottle, and flask should clearly list the substance, the hazard class, and the date it was poured or prepared. That sharpie and lab tape might not look high-tech, but they do more for your safety than any high-end sensor ever will.

When a spill happens, and eventually, one will, clear labeling can mean the difference between a quick fix and a dangerous guess.

Segregate Incompatibles

Not all chemicals play nice. Acids and bases stored too close can react violently. Flammables tucked on open shelving near heat sources? That’s a waiting game no one wants to play.

Segregate by class, not convenience. Use proper containers, and place flammables in cabinets designed to contain them. Many labs now build their layouts with safety in mind, and that includes using custom surfaces that help prevent cross-contamination. Splash guards, drain tops, and sloped worktops, like those we include in epoxy or phenolic resin work surfaces, aren’t aesthetic extras. They’re safety features.

Use Fume Hoods Correctly

Fume hoods are there for volatile compounds, not for convenience storage. Too often, they’re used as catchalls for supplies or neglected equipment. That’s a mistake.

Any chemical that off-gasses, vaporizes, or creates particles should be handled inside a functioning, ventilated hood. Make sure the sash is positioned properly, the airflow is on, and the interior isn’t overcrowded. And once the procedure’s done? Return your materials to safe storage, don’t treat the hood as a shelf.

DIY Lab Safety? Budget Workarounds

Some setups are working with duct tape and prayer. If funding is tight or equipment is outdated, that doesn’t mean you’re out of options.

Start with what you can control. Use closed resin pegboards to safely dry and store glassware. Swap unstable benches for anti-vibration balance tables that reduce spills and measurement errors. Small changes like these upgrade your safety baseline without overhauling your budget.

If you can’t afford to retrofit the whole lab, reinforce the parts that carry the most risk.

Emergency Preparedness: Don’t Wait Until It’s Too Late

You won’t always see an accident coming, but how you prepare determines what happens next. Labs aren’t inherently dangerous, lack of planning is. And in high-pressure situations, it’s not instincts that save you. It’s systems.

Know Your Safety Gear

Every person in the lab should know three things without hesitation:

  1. Where the fire extinguisher is

  2. Where the eyewash station is

  3. Where the spill kit is

That knowledge shouldn’t live on a map. It should live in muscle memory.

Safety gear doesn’t end at emergency tools. Built-in equipment matters too. One often-overlooked feature? The sink. When you’re working with corrosive compounds, the wrong material breaks down fast. 

That’s why we provide epoxy resin sinks that stand up to harsh spills and fast cleanups.

Emergency Protocols & Drills

When something goes wrong, the best reaction is already rehearsed.
Got a chemical splash? Use the eyewash or safety shower and flush for a full 15 minutes, even if it feels like overkill.
Electrical issue or fire? Power down if it's safe, then pull the alarm.
Injury or exposure? Report it. All of it. Every time.

Too many labs skip drills or treat protocols as paperwork. But the labs that rehearse, repeat, and take it seriously are the ones that stay ahead of the accident curve.

Safety Cabinets Matter

There’s always one lab trying to store volatile materials on open shelving or in random drawers. And while it might feel like no big deal at the time, non-contained flammables, acids, and solvents can turn a minor issue into a facility-wide shutdown.

That’s why our safety cabinets are built to code and then some. They’re compliant with OSHA, NFPA, SEFA, and UFC standards. Multiple sizes, secure door options, and proper ventilation all baked in. Because safe storage isn't a luxury, it’s a baseline.

Behavior & Culture: Making Labs Safer for Everyone

The rules posted on the wall only work if the people in the room respect them. Lab safety starts with layout and gear, but it lives, or dies, in behavior. Tools don’t cause accidents. People do.

No Horseplay, No Headphones

The lab isn’t a place to unwind. Every flammable, corrosive, or volatile material assumes you’re paying attention. Distraction is one of the biggest drivers of avoidable incidents, and horseplay, or even casual background music, can lower awareness faster than most realize.

Wearing headphones, for example, disconnects you from your environment. You can’t hear glass shatter. You miss verbal warnings. You lose track of nearby reactions. Whether it’s solo work or team experiments, full situational awareness isn’t optional.

If sound helps with focus, choose a controlled environment where speakers are allowed and others are on board. Otherwise, stay alert and stay audible.

Communicate Like a Pro

Let someone know where you are and how long you’ll be there. Use a text check-in system, and if available, lone-worker safety devices. These aren't about micromanagement, they're about making sure someone notices if something goes wrong.

The best labs operate like teams, not islands. And that starts with basic communication.

Leading by Example

Inconsistent rule enforcement undermines every protocol in place. If students see one person skip gloves or handle solvents barehanded, the takeaway is clear: the rules aren’t enforced, so they don’t matter.

That’s where leadership matters most. Educators, managers, and supervisors must walk the talk. They model the standard, not because it looks good, but because that’s what prevents near-misses from turning into incidents.

Culture is the multiplier. A well-equipped lab with no accountability is more dangerous than a modest one that runs tight procedures. Safety isn’t a vibe. It’s a chain of habits, and it only holds if everyone pulls their weight.

What Most Lab Safety Guides Miss (But You Shouldn’t)

Most lab safety checklists hit the same points: goggles, gloves, don’t mix chemicals you can’t pronounce. But they rarely talk about the things that quietly contribute to, or prevent, disaster. The space itself.

Surface Materials Make or Break Safety

If you’re working with corrosives, flammables, or thermal processes, the wrong countertop turns routine use into slow failure. Wood warps. Laminates peel. Budget plastic reacts. None of that happens with lab-grade epoxy or phenolic resin.

These materials are chemically resistant, heat-tolerant, and designed to take abuse without degradation.

Balance Tables Keep You Accurate, and Safe

Precision work doesn’t happen on wobbly legs. When you’re weighing volatile or reactive materials, even the smallest vibration can throw off your measurements, or worse, tip a container. That’s why we offer anti-vibration balance tables built to hold stable under stress. They absorb motion, stay put, and protect both your data and your labmates.

Seamless Stainless Steel Cuts Contamination

Gaps and seams collect residue. That’s a problem in any setting, but especially where sterility and chemical control matter. Our stainless steel countertops can be built up to 16 feet long without a seam, wide, wipeable, and custom-fitted to your layout. That means fewer cracks, faster cleanup, and lower risk of cross-contamination.

Design Safety Into the Quote

The best labs don’t retrofit safety after installation, they build it in from day one. That’s why every quote we deliver is custom, based on your specs. Whether it’s sink cutouts, utility holes, beveled or marine edges, or splash control, we make sure it’s built right the first time.

Our request-a-quote system exists to simplify that. No guessing. No compromise. Just a safer workspace that fits the job from the start.

Safe Lab Practices Checklist (Printable)

Sometimes you don’t need another lecture, you just need a clear, solid checklist to keep things tight. Print this. Post it. Use it before every session. Safety doesn’t start with best intentions. It starts with routine.

PPE Checklist

  • Lab coat on, sleeves secured

  • Chemical-resistant gloves in good condition

  • Sealed goggles (no open sides)

  • Closed-toe shoes (no sandals, no mesh)

  • Hair tied back, no loose jewelry, no acrylic nails

  • Contacts disclosed or protective eyewear adjusted

Workspace Checklist

  • Benches cleared of non-essential items

  • No food, drink, or personal items near work area

  • All tools and glassware on pegboards or returned to storage

  • Sinks clean and dry

  • Work surfaces wiped down (before and after use)

Chemical Handling Checklist

  • All containers clearly labeled (name, hazard, date)

  • Incompatibles stored separately

  • Flammables placed in certified safety cabinets

  • Fume hood operational and not used as storage

  • Spill kit, neutralizers, and MSDS sheets accessible

  • Surfaces are chemical-resistant (like epoxy or phenolic)

Emergency Gear Checklist

  • Fire extinguisher visible and unblocked

  • Eye wash and safety shower accessible

  • Emergency contact list posted

  • Know how to flush and report an incident

  • Safety cabinets compliant and closed securely (shop certified options)

Culture & Behavior Checklist

  • No headphones or horseplay

  • Everyone informed if working alone

  • Protocols are followed, not improvised

  • Team leads set the standard

  • Reminders or retraining offered if needed

This checklist works because it covers what people forget, not just what’s obvious. A safer lab starts with habits, not hardware. But when you do need the right gear, make sure it’s built for safety from the ground up.

Safety Is a System, Not a Suggestion

The labs that run safest are smart. Don’t you want a smart lab? 

  • They use work surfaces that resist chemical damage.

  • They invest in pegboards that keep glassware off crowded benches.

  • They lean on anti-vibration tables to prevent spills before they start. They quote their projects with safety in mind, down to the last faucet cutout.

If your lab doesn’t do these things yet, it’s time to shift from reactive to proactive. Start by upgrading the infrastructure that supports your protocols. Request a quote today and let us help build the kind of lab that keeps people safe, and gets real work done.

👉 Request a custom quote for safety-optimized lab gear